Paper and board - Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
NORM herausgegeben am 1.9.2014
Bezeichnung normen: ČSN EN 16418
Zeichen: 500430
Katalog-Nummer: 95616
Ausgabedatum normen: 1.9.2014
Zahl der Seiten: 24
Gewicht ca.: 72 g (0.16 Pfund)
Land: Tschechische technische Norm
Kategorie: Technische Normen ČSN
This European Standard specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line. Compared to the EN 15845[1], HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism